Phonon antibunching effect in coupled nonlinear micro/nanomechanical resonator at finite temperature

In this study, we investigate the phonon antibunching effect in a coupled nonlinear micro/nanoelectromechanical system (MEMS/NEMS) resonator at a finite temperature. In the weak driving limit, the optimal condition for phonon antibunching is given by solving the stationary Liouville-von Neumann master equation. We show that at low temperature, the phonon antibunching effect occurs in the regime of weak nonlinearity and mechanical coupling, which is confirmed by analytical and numerical solutions. We also find that thermal noise can degrade or even destroy the antibunching effect for different mechanical coupling strengths. Furthermore, a transition from strong antibunching to bunching for phonon correlation has been observed in the temperature domain. Finally, we find that a suitably strong driving in the finite-temperature case would help to preserve an optimal phonon correlation against thermal noise.Comment: 7 pages, 7 figur

The structure and energetics of Cr(CO)6 and Cr(CO)5

The geometric structure of Cr(CO)6 is optimized at the modified coupled pair functional (MCPF), single and double excitation coupled-cluster (CCSD) and CCSD(T) levels of theory (including a perturbational estimate for connected triple excitations), and the force constants for the totally symmetric representation are determined. The geometry of Cr(CO)5 is partially optimized at the MCPF, CCSD, and CCSD(T) levels of theory. Comparison with experimental data shows that the CCSD(T) method gives the best results for the structures and force constants, and that remaining errors are probably due to deficiencies in the one-particle basis sets used for CO. The total binding energies of Cr(CO)6 and Cr(CO)5 are also determined at the MCPF, CCSD, and CCSD(T) levels of theory. The CCSD(T) method gives a much larger total binding energy than either the MCPF or CCSD methods. An analysis of the basis set superposition error (BSSE) at the MCPF level of treatment points out limitations in the one-particle basis used. Calculations using larger basis sets reduce the BSSE, but the total binding energy of Cr(CO)6 is still significantly smaller than the experimental value, although the first CO bond dissociation energy of Cr(CO)6 is well described. An investigation of 3s3p correlation reveals only a small effect. In the largest basis set, the total CO binding energy of Cr(CO)6 is estimated to be 140 kcal/mol at the CCSD(T) level of theory, or about 86 percent of the experimental value. The remaining discrepancy between the experimental and theoretical value is probably due to limitations in the one-particle basis, rather than limitations in the correlation treatment. In particular an additional d function and an f function on each C and O are needed to obtain quantitative results. This is underscored by the fact that even using a very large primitive set (1042 primitive functions contracted to 300 basis functions), the superposition error for the total binding energy of Cr(CO)6 is 22 kcal/mol at the MCPF level of treatment

Share Food With Love

The home experience of serving food for friends and family, and sharing food is a significant event in my life. Furnishings play a prominent role in this circumstance. For my thesis, I created works that enhance the conditions and ambiance of the residential dining and living experience. When sharing with friends, happiness is my primary objective. I love to create works containing peacefulness and coziness that could help people calm down and relax. For my thesis body of work, I incorporated gentle curvilinear lines and symmetric shapes to suggest peaceful and harmonious feelings. My material choice was wood as the primary material, along with other materials, selected for reasons of contemporary aesthetics and appropriate function. I took advantage of colors and textures coming naturally from the materials. To invite users to enjoy my work, I created smooth, continuous and tactile surfaces. Each piece of my design was based on the research into lifestyle and dining culture. Creating furniture and other objects that help bring people together through the ritual of the dining experience was my goal. My aesthetics is influenced profoundly by Scandinavian design because of my summer experience in Denmark, 2015. Seven weeks was not a long period in a lifetime, but it was long enough to get a sense to begin with. I started to know a new environment with a deep history of modern design, and refreshed my mind. I researched the Scandinavian influential designers, such as Alvar Aalto, Finn Juhl, Arne Jacobsen, Bruno Mathsson, etc. I also researched furniture brands and designers world-wide to study what is timeless and what is happening currently, such as Michael Thonet, Charles and Ray Eames, and brands like Vitra, Carl Hansen & Søn, Design Within Reach, Normann Copenhagen, and Menu. My sources also included leading design and lifestyle magazines about travel, food, design and culture, such as Monocle, Wallpaper, Cereal Magazine, Elle Decor, Rum Interior Magazine, and Gentle Woman

Buck Converter

The recent sustainable energy growth triggered a huge power electronics demand, specifically related to power conversion. My senior project is a design of a buck converter which steps down the voltage from photovoltaic cells ranging from 5 to 40V to a rechargeable battery with 5V. This converter has a high enough power efficiency to effectively convert the energy harnessed from PV panels

INVESTIGATION OF THE ROLE OF GLYPICAN 3 IN LIVER REGENERATION AND HEPATOCYTE PROLIFERATION

Glypican 3 (GPC3) belongs to a family of glycosylphosphatidylinositol-anchored, cell-surface heparan sulfate proteoglycans. The GPC3 gene is located on the X chromosome, and is highly expressed during embryogenesis and organogenesis. Loss-of-function mutations of GPC3 in humans result in the Simpson-Golabi-Behmel syndrome, an X-linked disorder characterized by pre- and post-natal liver and other organ overgrowth. GPC3 is one of the most over-expressed proteins in human hepatocellular carcinoma and is used as a novel diagnostic marker. However, its role in normal liver regeneration is still not well characterized. In this study, we investigated the role and effects of GPC3 in hepatocyte proliferation and liver regeneration, using 2/3 partial hepatectomy (PHx) model in rats and hepatocyte-targeted GPC3 transgenic mice. We found in rats that GPC3 mRNA and protein increase in a time frame which coincides with the termination of proliferative activities of either hepatocytes (day 2 after PHx and day 8-12 in culture) or non-parenchymal cells (day 5-6 after PHx). Blocking GPC3 expression using morpholino oligonucleotides promoted rat hepatocyte growth in vitro. We further generated GPC3 transgenic mice with hepatocyte-targeted over-expression of GPC3. These transgenic mice develop normally compared with their non-transgenic littermates, but have a suppressed rate of hepatocyte proliferation and liver regeneration after 2/3 PHx. Therefore we hypothesize that GPC3 is a negative regulator of hepatocyte proliferation and liver regeneration. The yeast two-hybrid assay revealed that GPC3 interacts with several interesting proteins including CD81, a cell membrane tetraspanin. CD81 levels changed in the same manner as GPC3 after rat PHx, and their interaction was confirmed by co-immunoprecipitation and co-immunofluorescence. The co-localization of GPC3 and CD81 after PHx indicates an important regulator interaction between the two proteins. Moreover, gene array analysis revealed a series of changes in the expression profiles in GPC3 transgenic mice. After PHx, a panel of cell cycle related genes and some oncogenes are either up- or down-regulated, which was confirmed by western blotting. Our results indicate that GPC3 plays a negative regulatory role in hepatocyte proliferation and liver regeneration in rats and hepatocyte-targeted transgenic mice, in which several potential proteins and multiple pathways are involved and affected